ABSTRACT Cardiac sarcoidosis (CS) is a potentially severe manifestation of systemic sarcoidosis, associated with advanced atrioventricular block, ventricular arrhythmias, heart failure, and sudden death. Diagnosis remains challenging due to phenotypic variability and the limitations of conventional diagnostic methods. Advances in imaging techniques, especially the combination of positron emission tomography/computed tomography (PET/CT) using 18F-FDG and cardiac magnetic resonance imaging (CMR), have revolutionized the diagnostic approach and therapeutic monitoring of CS. This article reviews current concepts of CS and its diagnosis, with […]

Clinical case We report the case of a 55-year-old male patient who was admitted to the hospital in July 2019 with sudden left hemiplegia, mitral systolic murmur 4+, and aortic systolic and diastolic murmurs 2+. He had a history of aortic valve replacement in 2015, with a mechanical prosthetic aortic valve (PAV) due to infective endocarditis (IE). Cranial computed tomography (CT) revealed a right frontoparietal hematoma (), and blood tests revealed hyperglycemia and elevated C-reactive protein. His electrocardiogram (ECG) showed […]

Abstract Ischemic heart disease (IHD) is an important cause of morbidity and mortality in women and men. This paper emphasizes the differences of IHD in women, focusing on the diagnostic investigation in its stable phase. The higher prevalence of atypical symptoms, anatomical differences, and adverse psychosocial aspects, in addition to the association of specific risk factors regarding obstetrical history, requires an accurate clinical assessment and a targeted diagnostic investigation that consider the limitations, as well as the positive and negative […]