Abstract Much of cardiovascular medicine has been built on evidence derived from predominantly White, male cohorts that do not reflect the diversity of the patient population. Consequently, reference values, devices, and algorithms may exhibit variable accuracy across groups, thereby compromising diagnostic precision. From the perspective of cardiovascular imaging, this review examines how underrepresentation in research translates into diagnostic inequities. We discuss scenarios where representation alters what imaging reveals: transthyretin amyloidosis associated with the Val142Ile variant in older adults of African […]