Abstract This case report presents a myocardial perfusion analysis in a 67-year-old asymptomatic male patient with known coronary artery disease (CAD) and multiple risk factors. While myocardial perfusion Imaging (MPI) with single-photon emission computed tomography (SPECT) revealed a 5% area of ischemia, the myocardial blood flow quantification assessment in a camera equipped with cadmium-zinc-telluride (CZT) detectors demonstrated a reduced global myocardial flow reserve (MFR) of 1.57. Coronary angiography confirmed extensive multivessel disease, including an 80% stenosis in the left anterior […]

Abstract Within the clinical spectrum of chronic coronary syndrome (CCS), the presence of coronary artery disease (CAD) alongside ventricular dysfunction has long been a focal point due to the lower survival rates seen in this population. Improving survival in these patients, whether through medications or interventions, is a key concern for clinical cardiologists. Previous observational studies suggested that myocardial viability (MV) could influence the effectiveness of revascularization strategies in patients with ventricular dysfunction. Thus, viability assessment became a standard practice […]

Abstract Coronary microvascular dysfunction (CMD) is a condition that has been increasingly recognized as a cause of angina, with prognostic importance in multiple cardiovascular processes, especially in women. It results from abnormalities in the structure and/or function of the coronary microcirculation. Even in the absence of obstructive coronary artery disease (CAD), CMD is associated with worse prognosis, greater morbidity, impaired quality of life, and recurrent hospitalizations due to angina and heart failure, posing a challenge for diagnosis and treatment. In […]

Discussion Anomalous origin and course of coronary arteries are rare congenital heart diseases, affecting less than 1% of the general population., Anomalous coronary origin with an interarterial (suprapulmonary) course is characterized by the course of the coronary artery between the ascending aorta and the pulmonary artery trunk, most commonly involving the right coronary artery., Most individuals are asymptomatic, but, among symptomatic patients, chest pain and dyspnea on exertion are the most prevalent complaints. There is also an increase in rates […]

Abstract Ischemic heart disease (IHD) is an important cause of morbidity and mortality in women and men. This paper emphasizes the differences of IHD in women, focusing on the diagnostic investigation in its stable phase. The higher prevalence of atypical symptoms, anatomical differences, and adverse psychosocial aspects, in addition to the association of specific risk factors regarding obstetrical history, requires an accurate clinical assessment and a targeted diagnostic investigation that consider the limitations, as well as the positive and negative […]

Abstract Background Coronary computed tomography angiography is a noninvasive anatomic test for the diagnosis of coronary artery disease. The coronary fractional flow reserve is the gold standard method to determine if coronary stenosis is hemodynamically significant but requires an invasive procedure. Fractional flow reserve measurement by tomography is a new method to determine the hemodynamic significance of coronary luminal reduction. Objective To compare the accuracy of the invasive fractional flow reserve with the fractional flow reserve measurement by tomography. Method […]

Abstract Hypertrophic cardiomyopathy is the most common hereditary heart disease and affects about 1:500 individuals in the general population. Diagnosis is not always simple due to phenotypic variation and concomitance with other pathologies. It is initially based on electrocardiographic and echocardiographic criteria and on the absence of other diseases occurring with ventricular hypertrophy. Having myofibrillar derangement and fibrosis as a cellular base resulting in hemodynamic abnormalities, hypertrophic cardiomyopathy may reveal myocardial ischemia (not related to atherosclerosis) and sudden death. Therefore, […]