Abstract Heart Failure with Preserved Ejection Fraction (HFpEF) is an increasing challenge in cardiology, marked by impairments in systolic and/or diastolic function. HFpEF patients often present with exercise intolerance, yet diagnosis is complicated by overlapping comorbidities, such as obesity and hypertension. Left ventricular Global Longitudinal Strain (GLS) enables the detection of subtle systolic dysfunction, with studies indicating a stronger correlation between GLS and exercise capacity than ejection fraction (EF). In exercise echocardiography, GLS displays a characteristic bimodal pattern due to […]