Abstract Background: Chronic Chagas cardiomyopathy (CCC) manifests as heart failure, thromboembolic events, and sudden cardiac death (SCD). Although SCD may be the presenting event, there is still no recommendation for early cardioverter/defibrillator implantation in current guidelines. Objective: To evaluate the correlation between autonomic denervation, myocardial hypoperfusion, fibrosis, and ventricular arrhythmias in patients in the early stages of CCC. Methods: Cross-sectional study of 29 patients with CCC and preserved left ventricular function who underwent SPECT with iodine-123-meta-iodobenzylguanidine (123I-mIBG), myocardial perfusion SPECT […]